⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL150607 | 0.79 | — | — | |
| SCHEMBL1309332 | 0.78 | — | — | |
| SCHEMBL559559 | 0.77 | TAAR1 (0.56) | — | |
| SCHEMBL2030841 | 0.77 | TAAR1 (0.71) | — | |
| SCHEMBL919641 | 0.75 | — | — | |
| SCHEMBL1972145 | 0.74 | — | — | |
| SCHEMBL633673 | 0.74 | — | — | |
| SCHEMBL286875 | 0.74 | — | — | |
| SCHEMBL921269 | 0.74 | TAAR1 (0.59) | — | |
| SCHEMBL93009 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 899 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108440591-B | Synthesis method of chiral dihydrosilane compound | 浙江大学 | 2021-03-05 | — | — | CN | claimed |
| CN-107624113-B | Tetrahydropyridopyrimidines and tetrahydropyridopyridines as inhibitors of HBsAg (HBV surface antigen) and HBV DNA production for the treatment of hepatitis B virus infection | 豪夫迈·罗氏有限公司 | 2020-10-23 | — | — | CN | claimed |
| CN-110112465-A | Electrolyte for battery with lithium-rich manganese-based positive electrode material system and lithium ion battery | 东莞东阳光科研发有限公司 | 2019-08-09 | — | — | CN | claimed |
| US-20190010159-A1 | NOVEL KINASE INHIBITOR AGAINST WILD-TYPE AND MUTANT EGFR | PRECEDO PHARMACEUTICALS CO., LTD (CN) | 2019-01-10 | — | — | US | claimed |
| EP-3398950-A1 | NOVEL KINASE INHIBITOR AGAINST WILD-TYPE EGFR AND MUTATED EGFR | Precedo Pharmaceuticals Co., Ltd. (CN) | 2018-11-07 | — | — | EP | claimed |
| EP-2731436-B1 | 2-(PYRROLO[2,3-B]PYRIDINE-5-YL)-2-(T-BUTOXY)-ACETIC ACID DERIVATIVES AS HIV REPLICATION INHIBITORS FOR THE TREATMENT OF AIDS | VIIV HEALTHCARE UK LTD (GB) | 2017-03-08 | — | — | EP | claimed |
| US-9163023-B2 | Compounds and methods for treating HIV | VIIV HEALTHCARE UK LIMITED (GB) | 2015-10-20 | — | — | US | claimed |
| US-20150191469-A1 | COMPOUNDS AND METHODS FOR TREATING HIV | VIIV HEALTHCARE UK LIMITED (GB) | 2015-07-09 | — | — | US | claimed |
| EP-2877468-A1 | COMPOUNDS AND METHODS FOR TREATING HIV | VIIV Healthcare UK Limited (GB) | 2015-06-03 | — | — | EP | claimed |
| US-9029391-B2 | Isoquinoline compounds and methods for treating HIV | VIIV HEALTHCARE UK LIMITED (GB) | 2015-05-12 | — | — | US | claimed |
| US-5262416-A | Insecticides or fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1993-11-16 | — | — | US | claimed |
| US-5244865-A | Herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1993-09-14 | — | — | US | claimed |
| WO-1992017475-A1 | HETEROCYCLIC-CYCLIC AMINE DERIVATIVES | PFIZER INC. (US) | 1992-10-15 | — | — | WO | claimed |
| EP-0508954-A1 | Receiving element for thermal transfer printing | CIBA-GEIGY AG (CH) | 1992-10-14 | — | — | EP | claimed |
| EP-0441517-A2 | Tricyclic amines as novel cholinesterase inhibitors | PFIZER INC. (US) | 1991-08-14 | — | — | EP | claimed |
| EP-0439785-A2 | Substituted 2-[6-(pyrimidinyl)-indol-1-yl]-acrylic acid ester | BAYER AG (DE) | 1991-08-07 | — | — | EP | claimed |
| US-4530925-A | Aminocyclopentane esters and pharmaceutical formulations | GLAXO GROUP LIMITED (GB) | 1985-07-23 | — | — | US | claimed |
| EP-0127930-A2 | Aminocyclopentane esters and their preparation and pharmaceutical formulation | GLAXO GROUP LIMITED (GB) | 1984-12-12 | — | — | EP | claimed |
| US-4440682-A | Stereospecific synthesis of isocephalosporins and 2-oxa isocephalosporins | LABORATORIO FARMACEUTICO QUIMICO "LAFARQUIM, S.A." (ES) | 1984-04-03 | — | — | US | claimed |
| US-4265882-A | Sulphur analogs of penicillins having a nucleophile substituted in the 6 and 7 position, respectively | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1981-05-05 | — | — | US | claimed |