Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INSR | P06213 | 10/20 | 0.56 |
| ▸ | ALK | Q9UM73 | 6/20 | 0.56 |
| ▸ | MET | P08581 | 6/20 | 0.54 |
| ▸ | SYK | P43405 | 2/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 3/20 | 0.45 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.45 |
| ▸ | IDH1 | O75874 | 1/20 | 0.43 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.42 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26621718 | 0.90 | INSR (0.50) | INSRALKMETBRD4TRIM24 | |
| SCHEMBL30661466 | 0.90 | INSR (0.50) | INSRALKMETBRD4TRIM24 | |
| SCHEMBL26621561 | 0.90 | INSR (0.50) | INSRALKMETBRD4TRIM24 | |
| SCHEMBL30661645 | 0.84 | BRD4 (0.47) | INSRALKMETBRD4TYRO3 | |
| SCHEMBL23267171 | 0.82 | ROCK2 (0.57) | INSRALKMETSYK | |
| SCHEMBL1476799 | 0.79 | INSR (0.61) | INSRALKMETSYKBRD4 | |
| SCHEMBL27071763 | 0.79 | INSR (0.50) | INSRALKMETTRIM24 | |
| SCHEMBL1474806 | 0.78 | INSR (0.63) | INSRALKMETBRD4JAK2 | |
| SCHEMBL31444701 | 0.78 | BRD4 (0.43) | INSRALKMETBRD4TYRO3 | |
| SCHEMBL1475032 | 0.78 | INSR (0.68) | INSRALKMETBRD4JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025096710-A1 | MODULATORS OF BCL6 AS LIGAND DIRECTED DEGRADERS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-05-08 | — | — | WO | disclosed |