SCHEMBL31444682

SCHEMBL31444682

CNC(=O)CCn1ccc2ccc(Br)cc21

nearest known ligand 0.48

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HTR7 P34969 10/20 0.48
KMO O15229 2/20 0.48
PSMB1 P20618 2/20 0.46
PSMB5 P28074 2/20 0.46
MTNR1A P48039 3/20 0.44
MTNR1B P49286 3/20 0.44
FGFR1 P11362 1/20 0.42
FGFR4 P22455 1/20 0.42
LMNA P02545 1/20 0.41
NTSR1 P30989 1/20 0.41
HTR6 P50406 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22420998 0.83 KMO (0.70) HTR7KMOMTNR1AMTNR1BLMNA
SCHEMBL31444669 0.83 KMO (0.48) KMOMTNR1AMTNR1BLMNANTSR1
SCHEMBL26684010 0.82 KMO (0.68) HTR7KMOFGFR1FGFR4LMNA
Hydrochloric Acid SCHEMBL31444770 0.82 KMO (0.47) KMOMTNR1AMTNR1BLMNANTSR1
SCHEMBL25338684 0.77 HTR7 (0.48) HTR7KMOMTNR1AMTNR1BFGFR1
SCHEMBL7258387 0.77 KMO (0.57) HTR7KMOHTR6
SCHEMBL18239699 0.76 HTR7 (0.57) HTR7HTR6
SCHEMBL31121493 0.76 HTR7 (0.54) HTR7KMOFGFR1FGFR4HTR6
SCHEMBL5621531 0.76 HTR7 (0.54) HTR7KMOFGFR1FGFR4HTR6
SCHEMBL23631621 0.75 KMO (0.48) HTR7KMOFGFR1FGFR4HTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025096710-A1 MODULATORS OF BCL6 AS LIGAND DIRECTED DEGRADERS BRISTOL-MYERS SQUIBB COMPANY (US) 2025-05-08 WO disclosed