SCHEMBL31444690

SCHEMBL31444690

C[C@@H]1CN(c2nc(F)c(Cl)c(Nc3ccc4c(c3)CC(=O)N4C)n2)CC[C@H]1Nc1ccc2c(cnn2C2CCC(=O)NC2=O)c1

nearest known ligand 0.36

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ DDB1 Q16531 1/20 0.36
▸ CRBN Q96SW2 1/20 0.36
▸ IKZF2 Q9UKS7 5/20 0.32
▸ INSR P06213 2/20 0.31
▸ ALK Q9UM73 2/20 0.31
▸ SYK P43405 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31444600 0.91 BCL6 (0.37) DDB1CRBNINSRALK
SCHEMBL31444662 0.87 CRBN (0.35) DDB1CRBNIKZF2INSRALK
SCHEMBL26754546 0.83 DDB1 (0.46) DDB1CRBN
SCHEMBL31444594 0.83 BCL6 (0.39) —
SCHEMBL31444629 0.78 BCL6 (0.37) INSRALK
SCHEMBL27033171 0.76 DDB1 (0.46) DDB1CRBN
SCHEMBL31444549 0.76 INSR (0.39) INSRALK
SCHEMBL31702562 0.75 DDB1 (0.46) DDB1CRBNINSRALK
SCHEMBL31702423 0.75 DDB1 (0.46) DDB1CRBNINSRALK
SCHEMBL30661627 0.75 DDB1 (0.46) DDB1CRBNINSRALK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025096710-A1 MODULATORS OF BCL6 AS LIGAND DIRECTED DEGRADERS BRISTOL-MYERS SQUIBB COMPANY (US) 2025-05-08 — — WO disclosed
Send feedback