Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | PRKCI | P41743 | 1/20 | 0.38 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 3/20 | 0.37 |
| ▸ | CD63 | P08962 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.36 |
| ▸ | KARS1 | Q15046 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | IKBKB | O14920 | 1/20 | 0.35 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31444693 | 0.78 | HTT (0.43) | MAPTALDH1A1LMNASMN1; SMN2MAPK1 | |
| SCHEMBL31444553 | 0.72 | BRD4 (0.39) | MAPTSYKCD63 | |
| SCHEMBL8145613 | 0.69 | PRKCI (0.44) | MAPTALDH1A1KDM4ELMNAHSP90AB1 | |
| SCHEMBL20881858 | 0.66 | KMT2A (0.43) | MAPTALDH1A1KDM4ESMN1; SMN2MAPK1 | |
| SCHEMBL31554543 | 0.65 | NCF1 (0.47) | — | |
| SCHEMBL18584266 | 0.65 | RAD51 (0.44) | ALDH1A1KDM4ESMN1; SMN2HTTRAD51 | |
| SCHEMBL15218939 | 0.65 | NR4A1 (0.54) | MAPTALDH1A1KDM4ELMNANR4A1 | |
| SCHEMBL25114905 | 0.64 | SMN1; SMN2 (0.38) | MAPTALDH1A1KDM4EGAASMN1; SMN2 | |
| SCHEMBL15958647 | 0.63 | RAD51 (0.45) | MAPTALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL841311 | 0.63 | ALDH1A1 (0.36) | MAPTALDH1A1KDM4ESMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025096710-A1 | MODULATORS OF BCL6 AS LIGAND DIRECTED DEGRADERS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-05-08 | — | — | WO | disclosed |