Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ASPH | Q12797 | 1/20 | 0.33 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 4/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.32 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.31 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.31 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31445520 | 0.83 | AGBL2 (0.38) | AGBL2AKR1C3AKR1C2APPHCAR2 | |
| SCHEMBL10204646 | 0.77 | AGBL2 (0.32) | AGBL2SSTR4 | |
| SCHEMBL24608429 | 0.74 | MGLL (0.36) | SSTR4HDAC3HDAC1HDAC2PDK2 | |
| SCHEMBL29700897 | 0.74 | MGLL (0.36) | SSTR4HDAC3HDAC1HDAC2PDK2 | |
| SCHEMBL29750535 | 0.73 | P4HTM (0.42) | HDAC3HDAC1HDAC2 | |
| SCHEMBL24608426 | 0.73 | AGBL2 (0.31) | AGBL2 | |
| SCHEMBL22932532 | 0.72 | AGBL2 (0.32) | AGBL2 | |
| SCHEMBL31445203 | 0.72 | AGBL2 (0.38) | AGBL2AKR1C3AKR1C2APPHCAR2 | |
| SCHEMBL15204584 | 0.72 | AGBL2 (0.38) | AGBL2AKR1C3AKR1C2APPHCAR2 | |
| SCHEMBL29700926 | 0.71 | NAPRT (0.42) | AKR1C3AKR1C2APPKDM4ESLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072539-A1 | AMINO ACID COMPOUNDS WITH NITROGEN LINKERS AND USES THEREOF | PLIANT THERAPEUTICS, INC. (US) | 2025-04-03 | — | — | WO | disclosed |