Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.36 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.36 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | SPR | P35270 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | ELOVL1 | Q9BW60 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31446263 | 0.83 | APP (0.36) | AGBL2HDAC4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL15204492 | 0.81 | AKR1C3 (0.38) | AGBL2HDAC4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL30433944 | 0.80 | POLQ (0.35) | AGBL2HDAC4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL21408257 | 0.80 | POLQ (0.35) | AGBL2HDAC4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL31459534 | 0.73 | HDAC4 (0.61) | HDAC4AKR1C3AKR1C2AKR1C1AKR1B10 | |
| SCHEMBL31445374 | 0.73 | HDAC9 (0.32) | AKR1C1ABL1SPRHCAR2 | |
| SCHEMBL31446302 | 0.73 | AKR1C3 (0.41) | AGBL2HDAC4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL31446101 | 0.71 | AKR1C3 (0.39) | AGBL2AKR1C3AKR1C2AKR1C1APP | |
| SCHEMBL4979190 | 0.69 | PSEN1 (0.48) | HDAC4AKR1C3AKR1C2AKR1C1AKR1B10 | |
| SCHEMBL6032875 | 0.68 | AGBL2 (0.47) | AGBL2CYP2C9HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072539-A1 | AMINO ACID COMPOUNDS WITH NITROGEN LINKERS AND USES THEREOF | PLIANT THERAPEUTICS, INC. (US) | 2025-04-03 | — | — | WO | disclosed |