Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 6/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 6/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 5/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.36 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.35 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15572355 | 0.83 | AKR1C3 (0.40) | AKR1C3AKR1C2APPCYP2C19CYP2C9 | |
| SCHEMBL14974107 | 0.83 | AKR1C3 (0.40) | AKR1C3AKR1C2APPCYP2C19CYP2C9 | |
| SCHEMBL14973733 | 0.83 | AKR1C3 (0.43) | AKR1C3AKR1C2APPCYP2C19CYP2C9 | |
| SCHEMBL20241630 | 0.83 | AKR1C3 (0.40) | AKR1C3AKR1C2APPCYP2C19CYP2C9 | |
| SCHEMBL31446101 | 0.83 | AKR1C3 (0.39) | AKR1C3AKR1C2OPRL1APPCYP2C19 | |
| SCHEMBL15571680 | 0.81 | AKR1C3 (0.46) | AKR1C3AKR1C2APPAKR1C1AGBL2 | |
| SCHEMBL31446263 | 0.76 | APP (0.36) | AKR1C3AKR1C2APPCYP2C19CYP2C9 | |
| SCHEMBL31444975 | 0.73 | AGBL2 (0.41) | AKR1C3AKR1C2APPCYP2C19CYP2C9 | |
| SCHEMBL15204492 | 0.73 | AKR1C3 (0.38) | AKR1C3AKR1C2APPCYP2C19CYP2C9 | |
| SCHEMBL20241894 | 0.72 | AKR1C3 (0.41) | AKR1C3AKR1C2APPCYP2C19CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072539-A1 | AMINO ACID COMPOUNDS WITH NITROGEN LINKERS AND USES THEREOF | PLIANT THERAPEUTICS, INC. (US) | 2025-04-03 | — | — | WO | disclosed |