Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BUB1 | O43683 | 2/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | STS | P08842 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.33 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1809397 | 0.94 | GPR119 (0.38) | BUB1PIM1PIM2GPR119POLB | |
| SCHEMBL31445324 | 0.86 | POLB (0.36) | BUB1PIM1PIM2GPR119POLB | |
| SCHEMBL4247376 | 0.86 | GRM5 (0.39) | BUB1PIM1PIM2GPR119ESR2 | |
| SCHEMBL30646098 | 0.85 | BUB1 (0.38) | BUB1PIM1PIM2GPR119ESR2 | |
| SCHEMBL30133442 | 0.81 | ESR2 (0.41) | POLBKMT2AMEN1ESR2 | |
| SCHEMBL12654612 | 0.81 | ESR2 (0.41) | POLBKMT2AMEN1ESR2 | |
| SCHEMBL30684862 | 0.80 | PIM1 (0.40) | BUB1PIM1PIM2POLBKMT2A | |
| SCHEMBL3400140 | 0.80 | PIM1 (0.40) | BUB1PIM1PIM2POLBKMT2A | |
| SCHEMBL1808364 | 0.80 | ESR2 (0.41) | GPR119POLBKMT2AMEN1ESR2 | |
| SCHEMBL30168967 | 0.80 | ESR2 (0.41) | GPR119POLBKMT2AMEN1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072539-A1 | AMINO ACID COMPOUNDS WITH NITROGEN LINKERS AND USES THEREOF | PLIANT THERAPEUTICS, INC. (US) | 2025-04-03 | — | — | WO | disclosed |