Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.33 |
| ▸ | STS | P08842 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | GBA1 | P04062 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31445013 | 0.86 | BUB1 (0.38) | POLBKMT2AMEN1ESR2PIM1 | |
| SCHEMBL4245461 | 0.86 | GRM5 (0.39) | KMT2AMEN1ESR2PIM1PIM2 | |
| SCHEMBL1809397 | 0.83 | GPR119 (0.38) | POLBKMT2AMEN1ESR2PIM1 | |
| SCHEMBL30133442 | 0.78 | ESR2 (0.41) | POLBKMT2AMEN1ESR2KDM1A | |
| SCHEMBL12654612 | 0.78 | ESR2 (0.41) | POLBKMT2AMEN1ESR2KDM1A | |
| SCHEMBL30684862 | 0.77 | PIM1 (0.40) | POLBKMT2AMEN1ESR2PIM1 | |
| SCHEMBL3400140 | 0.77 | PIM1 (0.40) | POLBKMT2AMEN1ESR2PIM1 | |
| SCHEMBL30168967 | 0.77 | ESR2 (0.41) | POLBKMT2AMEN1ESR2HSP90AA1 | |
| SCHEMBL1808364 | 0.77 | ESR2 (0.41) | POLBKMT2AMEN1ESR2HSP90AA1 | |
| SCHEMBL26916024 | 0.74 | NOTUM (0.43) | KMT2AMEN1ESR2CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072539-A1 | AMINO ACID COMPOUNDS WITH NITROGEN LINKERS AND USES THEREOF | PLIANT THERAPEUTICS, INC. (US) | 2025-04-03 | — | — | WO | disclosed |