SCHEMBL31445142

SCHEMBL31445142

C[Si](C)(C)CCOCn1ncc(Cl)c1CC#N

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25048792 0.77 DGAT1 (0.34) DGAT1
Hydrochloric Acid SCHEMBL31618032 0.74 ALDH1A1 (0.31) DGAT1
SCHEMBL30940897 0.73 F2RL1 (0.33) DGAT1
SCHEMBL21521058 0.73 HTT (0.49)
SCHEMBL17239478 0.72 MGMT (0.31) DGAT1
SCHEMBL25075159 0.72 ALDH1A1 (0.40) DGAT1
SCHEMBL21519281 0.71 ALDH1A1 (0.40) DGAT1
SCHEMBL20899524 0.71 DGAT1 (0.35) DGAT1
SCHEMBL28903815 0.70 ATR (0.35) DGAT1
SCHEMBL25108475 0.70 F2RL1 (0.32) DGAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4642782-A2 ALPHA-V-BETA-8 INTEGRIN INHIBITORS AND USES THEREOF Pliant Therapeutics, Inc. (US) 2025-11-05 EP disclosed
WO-2025072539-A1 AMINO ACID COMPOUNDS WITH NITROGEN LINKERS AND USES THEREOF PLIANT THERAPEUTICS, INC. (US) 2025-04-03 WO disclosed