Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
| ▸ | HTR1B | P28222 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18202622 | 0.87 | KDM4E (0.52) | KDM4ERAB9ANPC1RECQLTAAR1 | |
| SCHEMBL19624156 | 0.80 | LMNA (0.41) | RAB9ANPC1RECQLKDM1ALMNA | |
| SCHEMBL18034939 | 0.77 | NPC1 (0.50) | RAB9ANPC1RECQLLMNAHDAC6 | |
| SCHEMBL7713782 | 0.77 | NPC1 (0.40) | KDM4ERAB9ANPC1RECQLKDM1A | |
| SCHEMBL13402952 | 0.77 | HTR7 (0.47) | KDM4EHTR1BLTA4H | |
| SCHEMBL29761634 | 0.77 | HTT (0.46) | RAB9ANPC1RECQLLMNAALDH1A1 | |
| SCHEMBL13576998 | 0.77 | HTT (0.46) | RAB9ANPC1RECQLLMNAALDH1A1 | |
| SCHEMBL10809447 | 0.76 | KDM4E (0.42) | KDM4ERAB9ATAAR1ALDH1A1HTR1B | |
| SCHEMBL20173484 | 0.76 | KDM4E (0.42) | KDM4ERAB9ATAAR1HTR1BTP53 | |
| SCHEMBL18291647 | 0.76 | HTR1B (0.46) | KDM4ERAB9ANPC1RECQLKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072539-A1 | AMINO ACID COMPOUNDS WITH NITROGEN LINKERS AND USES THEREOF | PLIANT THERAPEUTICS, INC. (US) | 2025-04-03 | — | — | WO | disclosed |