Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 5/20 | 0.72 |
| ▸ | ICAM1 | P05362 | 5/20 | 0.72 |
| ▸ | ITGAL | P20701 | 5/20 | 0.72 |
| ▸ | ITGB1 | P05556 | 8/20 | 0.60 |
| ▸ | ITGA4 | P13612 | 7/20 | 0.60 |
| ▸ | GAA | P10253 | 5/20 | 0.50 |
| ▸ | ITGAV | P06756 | 2/20 | 0.50 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ITGB8 | P26012 | 1/20 | 0.48 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.48 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31445679 | 0.90 | ITGB2 (0.57) | ITGB2ICAM1ITGALITGB1ITGA4 | |
| SCHEMBL31445626 | 0.90 | ITGB2 (0.68) | ITGB2ICAM1ITGALITGB1ITGA4 | |
| SCHEMBL14532631 | 0.86 | ITGB2 (0.76) | ITGB2ICAM1ITGALITGB1ITGA4 | |
| SCHEMBL31447160 | 0.84 | ITGA4 (0.58) | ITGB2ICAM1ITGALITGB1ITGA4 | |
| SCHEMBL31444766 | 0.81 | ITGA4 (0.60) | ITGB2ICAM1ITGALITGB1ITGA4 | |
| SCHEMBL31446197 | 0.81 | ITGB2 (0.54) | ITGB2ICAM1ITGALITGB1ITGA4 | |
| SCHEMBL3877117 | 0.81 | ITGB2 (0.65) | ITGB2ICAM1ITGALITGB1ITGA4 | |
| SCHEMBL31446653 | 0.81 | TAS1R3 (0.52) | ITGB2ICAM1ITGALITGB1ITGA4 | |
| SCHEMBL19523034 | 0.80 | ITGB2 (0.53) | ITGB2ICAM1ITGALGAAPOLB | |
| SCHEMBL5022118 | 0.79 | HPGD (0.59) | ITGB2ICAM1ITGALGAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072539-A1 | AMINO ACID COMPOUNDS WITH NITROGEN LINKERS AND USES THEREOF | PLIANT THERAPEUTICS, INC. (US) | 2025-04-03 | — | — | WO | disclosed |