Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | GRN | P28799 | 2/20 | 0.38 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.38 |
| ▸ | MME | P08473 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31445676 | 0.86 | PIK3CD (0.44) | MAPTGRNSORT1POLBNOD1 | |
| SCHEMBL19751451 | 0.85 | HPGD (0.33) | MAPTHPGDGAARAB9AGRN | |
| SCHEMBL31446958 | 0.85 | POLB (0.36) | MAPTGRNSORT1POLBNOD1 | |
| SCHEMBL31447158 | 0.82 | POLB (0.37) | MAPTPOLBNOD1MMESMN1; SMN2 | |
| SCHEMBL12427376 | 0.82 | CA2 (0.53) | MAPTHPGDGAARAB9AGRN | |
| SCHEMBL14009444 | 0.82 | CA2 (0.53) | MAPTHPGDGAARAB9AGRN | |
| SCHEMBL13127074 | 0.82 | MAPT (0.38) | MAPTHPGDGAARAB9AGRN | |
| SCHEMBL31446849 | 0.82 | MEN1 (0.35) | MAPTGRNSORT1POLBNOD1 | |
| SCHEMBL31445277 | 0.82 | EGLN1 (0.37) | MAPTGRNSORT1POLBNOD1 | |
| SCHEMBL31445682 | 0.82 | TGFBR1 (0.36) | MAPTGRNSORT1POLBNOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072539-A1 | AMINO ACID COMPOUNDS WITH NITROGEN LINKERS AND USES THEREOF | PLIANT THERAPEUTICS, INC. (US) | 2025-04-03 | — | — | WO | disclosed |