SCHEMBL3144782

SCHEMBL3144782

FOC(F)(C(F)(F)C(F)(F)C(F)(F)F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.40

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.40
THRB P10828 1/20 0.33
CA2 P00918 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3141748 0.90 LMNA (0.38) LMNATHRB
SCHEMBL3145634 0.90 LMNA (0.38) LMNATHRB
SCHEMBL31582089 0.76 LMNA (0.42) LMNATHRBCA2
SCHEMBL20417 0.73 LMNA (0.40) LMNATHRBCA2
SCHEMBL15893588 0.73 LMNA (0.40) LMNATHRBCA2
SCHEMBL984715 0.73 LMNA (0.61) LMNATHRBCA2
SCHEMBL1779065 0.73 LMNA (0.61) LMNATHRBCA2
SCHEMBL1924377 0.73 LMNA (0.61) LMNATHRBCA2
Perflexane SCHEMBL3671912 0.73 LMNA (0.61) LMNATHRBCA2
Perflexane SCHEMBL20769778 0.73 LMNA (0.61) LMNATHRBCA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1514968-B9 LEATHERY SHEET OBJECT AND PROCESS FOR PRODUCING THE SAME TEIJIN CORDLEY LTD (JP) 2010-02-17 EP disclosed
EP-1514968-B1 LEATHERY SHEET OBJECT AND PROCESS FOR PRODUCING THE SAME TEIJIN CORDLEY LTD (JP) 2008-12-17 EP disclosed
US-20050090169-A1 Leathery sheet object, process for producing the same, and urethane compound modified with flurinated side chain TEIJIN CORDLEY LIMITED (JP) 2005-04-28 US disclosed
EP-1514968-A1 LEATHERY SHEET OBJECT, PROCESS FOR PRODUCING THE SAME, AND URETHANE COMPOUND MODIFIED WITH FLUORINATED SIDE CHAIN Teijin Cordley Limited (JP) 2005-03-16 EP disclosed