Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | MMP1 | P03956 | 2/20 | 0.38 |
| ▸ | MMP2 | P08253 | 2/20 | 0.38 |
| ▸ | MMP9 | P14780 | 2/20 | 0.38 |
| ▸ | MMP8 | P22894 | 2/20 | 0.38 |
| ▸ | MMP13 | P45452 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Perflenapent SCHEMBL7648533 | 1.00 | LMNA (0.61) | LMNATHRBCA2CA1MMP1 | |
| SCHEMBL984715 | 1.00 | LMNA (0.61) | LMNATHRBCA2CA1MMP1 | |
| SCHEMBL3743142 | 1.00 | LMNA (0.61) | LMNATHRBCA2CA1MMP1 | |
| SCHEMBL1924377 | 1.00 | LMNA (0.61) | LMNATHRBCA2CA1MMP1 | |
| SCHEMBL1707474 | 1.00 | LMNA (0.61) | LMNATHRBCA2CA1MMP1 | |
| Perflexane SCHEMBL7507426 | 1.00 | LMNA (0.61) | LMNATHRBCA2CA1MMP1 | |
| SCHEMBL1779065 | 1.00 | LMNA (0.61) | LMNATHRBCA2CA1MMP1 | |
| SCHEMBL771546 | 1.00 | LMNA (0.61) | LMNATHRBCA2CA1MMP1 | |
| Perflexane SCHEMBL20769778 | 1.00 | LMNA (0.61) | LMNATHRBCA2CA1MMP1 | |
| Perflenapent SCHEMBL33962 | 1.00 | LMNA (0.61) | LMNATHRBCA2CA1MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2240104-A2 | RAPID COOLING OF BODY AND/OR BRAIN BY IRRIGATING AERODIGESTIVE TRACT WITH COOLING LIQUID | Neurosave Inc. (US) | 2010-10-20 | — | — | EP | disclosed |
| WO-2009094601-A2 | RAPID COOLING OF BODY AND/OR BRAIN BY IRRIGATING AERODIGESTIVE TRACT WITH COOLING LIQUID | KRECK THOMAS (US) | 2009-07-30 | — | — | WO | disclosed |