SCHEMBL31448322

SCHEMBL31448322

Nc1ccn([C@@]2(F)C[C@H](O)[C@@H](COP(=O)(O)O)O2)c(=O)n1

nearest known ligand 0.48

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.46
POLA1 P09884 2/20 0.44
PDE4D Q08499 1/20 0.41
PDE3A Q14432 1/20 0.41
SLC29A1 Q99808 1/20 0.41
P2RY2 P41231 4/20 0.39
P2RY4 P51582 3/20 0.39
P2RY6 Q15077 2/20 0.39
POLG P54098 1/20 0.38
TSHR P16473 1/20 0.36
GLA P06280 1/20 0.36
ST6GAL1 P15907 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25396644 0.91 POLG (0.51) POLBPOLA1P2RY2P2RY4P2RY6
SCHEMBL17027931 0.86 POLB (0.46) POLBPOLA1PDE4DPDE3ASLC29A1
SCHEMBL9328022 0.85 POLB (0.46) POLBPOLA1PDE4DPDE3ASLC29A1
SCHEMBL3038818 0.84 PDE3A (0.52) POLBPOLA1PDE4DPDE3ASLC29A1
SCHEMBL30194983 0.81 POLA1 (0.46) POLBPOLA1PDE4DPDE3ASLC29A1
SCHEMBL475344 0.80 P2RY6 (0.51) POLA1P2RY2P2RY4P2RY6
SCHEMBL3759574 0.80 POLA1 (0.44) POLBPOLA1PDE4DPDE3ASLC29A1
SCHEMBL6141746 0.78 POLG (0.51) POLBP2RY2P2RY4P2RY6POLG
SCHEMBL13234931 0.77 POLA1 (0.44) POLBPOLA1P2RY2P2RY4P2RY6
SCHEMBL12363580 0.77 POLA1 (0.44) POLBPOLA1P2RY2P2RY4P2RY6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119614654-A Enzymatic synthesis method of 2' -fluoro-2 ' -deoxynucleoside-5 ' -triphosphate and application thereof 华南理工大学 2025-03-14 CN disclosed