Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 2/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | NPY1R | P25929 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31571 | 0.81 | AAK1 (0.57) | AAK1XDHSLC22A12 | |
| SCHEMBL6627537 | 0.80 | AR (0.40) | ALDH1A1ACHETSHRRAB9ANPY1R | |
| SCHEMBL7695665 | 0.77 | AAK1 (0.51) | AAK1XDHSLC22A12MAOAMAOB | |
| SCHEMBL9477443 | 0.77 | AAK1 (0.51) | AAK1XDHSLC22A12MAOAMAOB | |
| SCHEMBL7695663 | 0.77 | AAK1 (0.51) | AAK1XDHSLC22A12MAOAMAOB | |
| SCHEMBL17155460 | 0.76 | AAK1 (0.58) | AAK1XDHSLC22A12MAOAMAOB | |
| SCHEMBL28986747 | 0.75 | AAK1 (0.49) | AAK1ALDH1A1XDHSLC22A12MAOA | |
| SCHEMBL2319042 | 0.75 | MEN1 (0.56) | KDM4ETDP1ALDH1A1TSHRNPY1R | |
| SCHEMBL392560 | 0.73 | MAOB (0.47) | AAK1ALDH1A1TSHRRAB9AXDH | |
| SCHEMBL28635630 | 0.72 | MBTD1 (0.38) | KDM4EALDH1A1ACHENOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119613384-A | 2-Amino substituted aza-heteroaryl compounds as HPK1 inhibitors and uses thereof | 中国药科大学 | 2025-03-14 | — | — | CN | disclosed |