Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 5/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 7/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31571 | 0.86 | AAK1 (0.57) | AAK1XDHSLC22A12 | |
| SCHEMBL7695663 | 0.82 | AAK1 (0.51) | AAK1MAOAMAOBXDHSLC22A12 | |
| SCHEMBL7695665 | 0.82 | AAK1 (0.51) | AAK1MAOAMAOBXDHSLC22A12 | |
| SCHEMBL17155460 | 0.81 | AAK1 (0.58) | AAK1MAOAMAOBXDHSLC22A12 | |
| SCHEMBL28986747 | 0.81 | AAK1 (0.49) | AAK1MAOAMAOBXDHSLC22A12 | |
| SCHEMBL3578378 | 0.78 | XDH (0.51) | AAK1MAOAMAOBXDHCYP3A4 | |
| SCHEMBL392560 | 0.78 | MAOB (0.47) | AAK1MAOAMAOBXDHAR | |
| SCHEMBL430108 | 0.77 | EGFR (0.47) | AAK1MAOAMAOBXDHAR | |
| SCHEMBL31448331 | 0.77 | AAK1 (0.47) | AAK1MAOAMAOBXDHSLC22A12 | |
| Hydrochloric Acid SCHEMBL27743340 | 0.76 | MAOB (0.46) | AAK1MAOAMAOBXDHAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5270308-A | Hypotensives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-12-14 | — | — | US | disclosed |