SCHEMBL3144873

SCHEMBL3144873

CC(=NO)c1cccnc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.59
GAA P10253 3/20 0.53
KMT2A Q03164 2/20 0.51
ALDH1A1 P00352 2/20 0.50
APP P05067 1/20 0.50
HCAR3 P49019 1/20 0.50
HCAR2 Q8TDS4 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
RAB9A P51151 2/20 0.49
MEN1 O00255 1/20 0.49
NPC1 O15118 1/20 0.49
ESR1 P03372 1/20 0.49
F7 P08709 1/20 0.48
F3 P13726 1/20 0.48
SARM1 Q6SZW1 1/20 0.48
SIRT2 Q8IXJ6 1/20 0.48
SIRT6 Q8N6T7 1/20 0.48
SIRT1 Q96EB6 1/20 0.48
SIRT3 Q9NTG7 1/20 0.48
SIRT5 Q9NXA8 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3144867 1.00 PKM (0.59) PKMGAAKMT2AALDH1A1APP
SCHEMBL10665182 1.00 PKM (0.59) PKMGAAKMT2AALDH1A1APP
SCHEMBL29509895 1.00 PKM (0.59) PKMGAAKMT2AALDH1A1APP
Hydrochloric Acid SCHEMBL27641130 0.98 PKM (0.57) PKMGAAKMT2AALDH1A1APP
Iodomethane SCHEMBL9502429 0.96 PKM (0.56) PKMGAAKMT2AALDH1A1APP
Iodomethane SCHEMBL9502426 0.96 PKM (0.56) PKMGAAKMT2AALDH1A1APP
SCHEMBL1254940 0.85 PKM (0.61) PKMGAAKMT2AALDH1A1APP
SCHEMBL6585602 0.83 PKM (0.59) PKMGAAKMT2AALDH1A1APP
SCHEMBL9769000 0.82 PKM (0.57) PKMGAAKMT2AALDH1A1APP
SCHEMBL8306869 0.80 MKNK1 (0.57) ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109705146-A 2- amino benzo [4,5] thieno [3,2-d] thiazole, derivative and its synthetic method 湘潭大学 2019-05-03 CN claimed
CN-108822135-A A kind of synthetic method of the cyclosubstituted thieno of azepine [3,2-d] thiazole and its derivative 湘潭大学 2018-11-16 CN claimed
WO-2025202955-A1 FUSED BICYCLIC COMPOUNDS AND THEIR USE AS PEST CONTROL AGENTS PI INDUSTRIES LTD. (IN) 2025-10-02 WO disclosed
CN-109705146-A 2- amino benzo [4,5] thieno [3,2-d] thiazole, derivative and its synthetic method 湘潭大学 2019-05-03 CN disclosed
CN-108822135-A A kind of synthetic method of the cyclosubstituted thieno of azepine [3,2-d] thiazole and its derivative 湘潭大学 2018-11-16 CN disclosed
EP-2927218-B1 TETRAZOLINONE COMPOUND AND USE THEREOF SUMITOMO CHEMICAL CO (JP) 2018-07-04 EP disclosed
EP-2927218-B1 TETRAZOLINONE COMPOUND AND USE THEREOF SUMITOMO CHEMICAL CO (JP) 2018-07-04 EP disclosed
US-9725423-B2 Tetrazolinone compound and applications thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-08-08 US disclosed
US-9725423-B2 Tetrazolinone compound and applications thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-08-08 US disclosed
US-9725423-B2 Tetrazolinone compound and applications thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-08-08 US disclosed
US-20150299146-A1 TETRAZOLINONE COMPOUND AND APPLICATIONS THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-10-22 US disclosed
US-5073561-A N-substituted-pyridinyl oximes WARNER-LAMBERT COMPANY (US) 1991-12-17 US disclosed
US-4929734-A ANTIINFLAMMATORY AGENTS, ANTIDEPRESSANTS WARNER-LAMBERT COMPANY (US) 1990-05-29 US disclosed
US-4798841-A COGNITION ACTIVATORS, ANALGESICS WARNER-LAMBERT COMPANY (US) 1989-01-17 US disclosed
EP-0291673-A1 Tetrahydropyridine oximes, a process for their preparation and use thereof as cholinergic agents WARNER-LAMBERT COMPANY (US) 1988-11-23 EP disclosed
EP-0288394-A2 1,2,5,6-Tetrahydropyridines, process for their preparation, their use as medicines and compositions containing them ROUSSEL-UCLAF (FR) 1988-10-26 EP disclosed
US-4710508-A ANALGESICS WARNER-LAMBERT COMPANY (US) 1987-12-01 US disclosed
US-4450270-A Dioximino cephalosporin antibiotics ELI LILLY AND COMPANY (US) 1984-05-22 US disclosed
US-4402955-A ZWITTERIONS; GRAMNEGATIVE BACTERIA ELI LILLY AND COMPANY (US) 1983-09-06 US disclosed
US-4379787-A ANTIBIOTICS ELI LILLY AND COMPANY (US) 1983-04-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150299146-A1 TETRAZOLINONE COMPOUND AND APPLICATIONS THEREOF RTN3, CYCS, ATL3 PKM 1739/4885GAA 4133/4885KMT2A 3298/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.