Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 18/20 | 0.90 |
| ▸ | BCL2 | P10415 | 9/20 | 0.90 |
| ▸ | MDM4 | O15151 | 1/20 | 0.90 |
| ▸ | BCL2L11 | O43521 | 1/20 | 0.90 |
| ▸ | TP53 | P04637 | 1/20 | 0.90 |
| ▸ | BID | P55957 | 1/20 | 0.90 |
| ▸ | BAX | Q07812 | 1/20 | 0.90 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.90 |
| ▸ | ASPH | Q12797 | 1/20 | 0.90 |
| ▸ | BECN1 | Q14457 | 1/20 | 0.90 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.90 |
| ▸ | BCL2L2 | Q92843 | 1/20 | 0.90 |
| ▸ | BAD | Q92934 | 1/20 | 0.90 |
| ▸ | BBC3 | Q9BXH1 | 1/20 | 0.90 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.79 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.79 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.79 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.79 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.79 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26648832 | 1.00 | BCL2L1 (0.90) | BCL2L1BCL2MDM4BCL2L11TP53 | |
| SCHEMBL26648001 | 1.00 | BCL2L1 (0.90) | BCL2L1BCL2MDM4BCL2L11TP53 | |
| SCHEMBL31450509 | 0.95 | BCL2L1 (0.88) | BCL2L1BCL2MDM4BCL2L11TP53 | |
| Abt 737 SCHEMBL29355185 | 0.95 | BCL2L1 (1.00) | BCL2L1BCL2MDM4BCL2L11TP53 | |
| Abt 737 SCHEMBL170470 | 0.95 | BCL2L1 (1.00) | BCL2L1BCL2MDM4BCL2L11TP53 | |
| SCHEMBL8516571 | 0.95 | BCL2L1 (0.89) | BCL2L1BCL2MDM4BCL2L11TP53 | |
| Abt 737 SCHEMBL1541072 | 0.95 | BCL2L1 (1.00) | BCL2L1BCL2MDM4BCL2L11TP53 | |
| SCHEMBL3426272 | 0.95 | BCL2L1 (0.89) | BCL2L1BCL2MDM4BCL2L11TP53 | |
| Abt 737 SCHEMBL158942 | 0.95 | BCL2L1 (1.00) | BCL2L1BCL2MDM4BCL2L11TP53 | |
| SCHEMBL1541099 | 0.94 | BCL2L1 (0.88) | BCL2L1BCL2MDM4BCL2L11TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260092057-A1 | BCL-XL/BCL-2 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS INC (US) | 2026-04-02 | — | — | US | disclosed |
| EP-4522154-A1 | BCL-XL/BCL-2 DEGRADERS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2025-03-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260092057-A1 | BCL-XL/BCL-2 DEGRADERS AND USES THEREOF | BCL2L2, BCL2A1, BCL2L1 | BCL2L1 3/4885BCL2 4/4885MDM4 3502/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.