Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 17/20 | 0.37 |
| ▸ | RET | P07949 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29151437 | 1.00 | KRAS (0.37) | KRASRETHDAC1 | |
| SCHEMBL31451806 | 0.88 | KRAS (0.41) | KRAS | |
| SCHEMBL30949859 | 0.88 | KRAS (0.41) | KRAS | |
| SCHEMBL31328546 | 0.84 | KRAS (0.40) | KRAS | |
| SCHEMBL31328675 | 0.84 | KRAS (0.40) | KRAS | |
| SCHEMBL29151485 | 0.84 | KRAS (0.40) | KRAS | |
| SCHEMBL31328693 | 0.84 | KRAS (0.40) | KRAS | |
| SCHEMBL31451752 | 0.81 | KRAS (0.39) | KRAS | |
| SCHEMBL30957194 | 0.80 | KRAS (0.41) | KRAS | |
| SCHEMBL29876081 | 0.80 | KRAS (0.44) | KRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025016899-A1 | SPIROCYCLIC COMPOUNDS FOR THE TREATMENT OF CANCER | BAYER AKTIENGESELLSCHAFT (DE) | 2025-01-23 | — | — | WO | disclosed |