Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 19/20 | 0.39 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31451806 | 0.94 | KRAS (0.41) | KRAS | |
| SCHEMBL30949859 | 0.94 | KRAS (0.41) | KRAS | |
| SCHEMBL27243616 | 0.84 | KRAS (0.42) | KRAS | |
| SCHEMBL31451700 | 0.81 | KRAS (0.37) | KRAS | |
| SCHEMBL29151437 | 0.81 | KRAS (0.37) | KRAS | |
| SCHEMBL25356505 | 0.81 | KRAS (0.42) | KRAS | |
| SCHEMBL30576899 | 0.81 | KRAS (0.42) | KRAS | |
| SCHEMBL31451746 | 0.81 | KRAS (0.47) | KRAS | |
| SCHEMBL31451914 | 0.80 | KRAS (0.37) | KRAS | |
| SCHEMBL25136924 | 0.80 | KRAS (0.42) | KRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025016899-A1 | SPIROCYCLIC COMPOUNDS FOR THE TREATMENT OF CANCER | BAYER AKTIENGESELLSCHAFT (DE) | 2025-01-23 | — | — | WO | disclosed |