Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 3/20 | 0.37 |
| ▸ | JAK1 | P23458 | 3/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.35 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31387849 | 0.92 | MEN1 (0.44) | CTSKMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL1476907 | 0.91 | USP2 (0.45) | CTSKMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL16414999 | 0.89 | CYP4F2 (0.41) | CTSKMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL2328812 | 0.88 | CTSK (0.43) | CTSKMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL16414783 | 0.86 | CTSK (0.40) | CTSKMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL89886 | 0.85 | CTSK (0.40) | CTSKMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL16415241 | 0.84 | CTSK (0.39) | CTSKMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL2798365 | 0.83 | USP2 (0.43) | CTSKMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL31171511 | 0.83 | CTSK (0.38) | CTSKMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL31171534 | 0.83 | CTSK (0.38) | CTSKMEN1ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025096637-A1 | SUBSTITUTED ARYL SULFONAMIDES FOR USE AS SODIUM CHANNEL INHIBITORS | XENON PHARMACEUTICALS INC. (CA) | 2025-05-08 | — | — | WO | disclosed |
| WO-2025016899-A1 | SPIROCYCLIC COMPOUNDS FOR THE TREATMENT OF CANCER | BAYER AKTIENGESELLSCHAFT (DE) | 2025-01-23 | — | — | WO | disclosed |