Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 4/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3143773 | 0.87 | FAAH (0.46) | FAAH | |
| SCHEMBL3144371 | 0.83 | FAAH (0.53) | HDAC1HDAC6FAAHCHRM2CHRM1 | |
| SCHEMBL3140214 | 0.82 | CHRM2 (0.40) | HDAC1HDAC6FAAHCHRM2CHRM1 | |
| SCHEMBL1471592 | 0.82 | FAAH (0.56) | FAAH | |
| SCHEMBL3140173 | 0.81 | FAAH (0.58) | FAAH | |
| SCHEMBL1471365 | 0.78 | FAAH (0.56) | FAAH | |
| SCHEMBL1471729 | 0.77 | FAAH (0.53) | HDAC1HDAC6FAAH | |
| SCHEMBL3136741 | 0.75 | FAAH (0.46) | FAAH | |
| SCHEMBL2163574 | 0.74 | FAAH (0.46) | FAAH | |
| SCHEMBL3132815 | 0.74 | FAAH (0.46) | FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8268817-B2 | Substituted oxazole ketone modulators of fatty acid amide hydrolase | THE SCRIPPS RESEARCH INSTITUTE (US) | 2012-09-18 | — | — | US | disclosed |
| US-20100075931-A1 | Substituted oxazole ketone modulators of fatty acid amide hydrolase | THE SCRIPPS RESEARCH INSTITUTE (US) | 2010-03-25 | — | — | US | disclosed |
| EP-2068862-A2 | SUBSTITUTED OXAZOLE KETONE MODULATORS OF FATTY ACID AMIDE HYDROLASE | The Scripps Research Institute (US) | 2009-06-17 | — | — | EP | disclosed |
| WO-2008030532-A2 | SUBSTITUTED OXAZOLE KETONE MODULATORS OF FATTY ACID AMIDE HYDROLASE | THE SCRIPPS RESEARCH INSTITUTE (US) | 2008-03-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100075931-A1 | Substituted oxazole ketone modulators of fatty acid amide hydrolase | FAAH, FAAH2, HCRTR2 | HDAC1 109/4885HDAC6 307/4885FAAH 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.