SCHEMBL31452006

SCHEMBL31452006

O=C(Oc1ccccc1)c1ncn2c(=O)n(CCOC(F)(F)F)nnc12

nearest known ligand 0.37

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.37
MEN1 O00255 1/20 0.37
PABPC1 P11940 1/20 0.37
GRM5 P41594 1/20 0.34
HDAC1 Q13547 2/20 0.33
HDAC2 Q92769 2/20 0.33
TP53 P04637 1/20 0.32
CA12 O43570 2/20 0.32
CA1 P00915 2/20 0.32
CA2 P00918 2/20 0.32
CA9 Q16790 2/20 0.32
KDM4C Q9H3R0 1/20 0.31
NPC1 O15118 1/20 0.31
ALDH1A1 P00352 1/20 0.31
PTGER4 P35408 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31451983 0.85 KMT2A (0.45) KMT2AMEN1PABPC1CA12CA1
SCHEMBL31452066 0.83 ALDH1A1 (0.43) KMT2AMEN1PABPC1TP53CA12
SCHEMBL31452100 0.82 MEN1 (0.41) KMT2AMEN1PABPC1TP53CA12
SCHEMBL31452096 0.82 MEN1 (0.44) KMT2AMEN1PABPC1CA12CA1
SCHEMBL31452072 0.82 MEN1 (0.41) KMT2AMEN1PABPC1CA12CA1
SCHEMBL31452056 0.82 MEN1 (0.56) KMT2AMEN1PABPC1CA12CA1
SCHEMBL31451975 0.81 PTGER4 (0.35) ALDH1A1PTGER4
SCHEMBL31452105 0.80 MEN1 (0.44) KMT2AMEN1PABPC1CA12CA1
SCHEMBL31452009 0.79 MEN1 (0.42) KMT2AMEN1PABPC1CA12CA1
SCHEMBL31452121 0.79 MEN1 (0.43) KMT2AMEN1PABPC1CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250066371-A1 FLUOROALKOXYALKYLENE-DIHYDROIMIDAZO[5,1-D]TETRAZINONE COMPOUNDS AND RELATED COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS MODIFI BIOSCIENCES, INC. 2025-02-27 US disclosed
WO-2025034537-A1 FLUOROALKOXYALKYLENE-DIHYDROIMIDAZO[5,1-D]TETRAZINONE COMPOUNDS AND RELATED COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS MODIFI BIOSCIENCES, INC. (US) 2025-02-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250066371-A1 FLUOROALKOXYALKYLENE-DIHYDROIMIDAZO[5,1-D]TETRAZINONE COMPOUNDS AND RELATED COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS PKD1, APC, VHL KMT2A 2741/4885MEN1 1199/4885PABPC1 4026/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.