Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.46 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.46 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | CDK8 | P49336 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5215089 | 0.79 | MAPK9 (0.56) | CYP3A4CYP2C9MEN1KMT2AALDH1A1 | |
| SCHEMBL30599018 | 0.79 | MAPK9 (0.56) | CYP3A4CYP2C9MEN1KMT2AALDH1A1 | |
| SCHEMBL28115994 | 0.75 | CYP3A4 (0.42) | CYP3A4CYP2C9CYP2E1CYP2A6CYP2B6 | |
| SCHEMBL9438562 | 0.71 | ALDH1A1 (0.46) | CYP3A4CYP2C9CYP2E1CYP2A6CYP2B6 | |
| SCHEMBL12096896 | 0.71 | KDM4E (0.51) | CYP3A4CYP2C9CYP2E1CYP2A6CYP2B6 | |
| SCHEMBL30418553 | 0.71 | KDM4E (0.51) | CYP3A4CYP2C9CYP2E1CYP2A6CYP2B6 | |
| SCHEMBL31452803 | 0.70 | MAPK9 (0.51) | CYP3A4CCNA2CDK2MEN1KMT2A | |
| SCHEMBL31452825 | 0.70 | ADORA1 (0.58) | CYP3A4CYP2C9CCNA2CDK2MEN1 | |
| SCHEMBL29521818 | 0.70 | MAPK9 (0.51) | CYP3A4CYP2C9MEN1KMT2AALDH1A1 | |
| SCHEMBL2275178 | 0.70 | MAPK9 (0.51) | CYP3A4MEN1KMT2AALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119735553-A | Substituted pyrimidine compound and preparation method and application thereof | 上海应用技术大学 | 2025-04-01 | — | — | CN | claimed |
| CN-119735553-A | Substituted pyrimidine compound and preparation method and application thereof | 上海应用技术大学 | 2025-04-01 | — | — | CN | disclosed |