Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | AVPR2 | P30518 | 3/20 | 0.50 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.50 |
| ▸ | OXTR | P30559 | 2/20 | 0.50 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10568480 | 0.84 | POLB (0.67) | ALDH1A1HPGDMEN1KMT2AAVPR2 | |
| SCHEMBL17544697 | 0.80 | NOTUM (0.59) | ALDH1A1HPGDMEN1KMT2AP2RX1 | |
| SCHEMBL11335480 | 0.80 | ATM (0.46) | ALDH1A1KMT2AP2RX1SMN1; SMN2POLB | |
| SCHEMBL29463754 | 0.78 | ALDH1A1 (0.81) | ALDH1A1HPGDMEN1KMT2AAVPR2 | |
| SCHEMBL6198498 | 0.78 | ALDH1A1 (0.81) | ALDH1A1HPGDMEN1KMT2AAVPR2 | |
| SCHEMBL1135622 | 0.78 | ALDH1A1 (0.56) | ALDH1A1HPGDMEN1KMT2AAVPR2 | |
| SCHEMBL11537014 | 0.77 | P2RX1 (0.50) | ALDH1A1HPGDMEN1KMT2AP2RX1 | |
| SCHEMBL11281614 | 0.73 | ALDH1A1 (0.42) | ALDH1A1HPGDMEN1KMT2ATSHR | |
| SCHEMBL6108617 | 0.73 | P2RX1 (0.50) | ALDH1A1HPGDMEN1KMT2AP2RX1 | |
| SCHEMBL7348349 | 0.73 | AVPR2 (0.76) | ALDH1A1HPGDMEN1KMT2AAVPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1751113-B1 | UREA ANTAGONISTS OF P2Y1 RECEPTOR USEFUL IN THE TREATMENT OF THROMBOTIC CONDITIONS | BRISTOL MYERS SQUIBB CO (US) | 2010-03-10 | — | — | EP | disclosed |
| US-7674828-B2 | Urea antagonists of P2Y1receptor useful in the treatment of thrombotic conditions | BRISTOL-MYERS SQUIBB COMPANY (US) | 2010-03-09 | — | — | US | disclosed |
| US-20080280905-A1 | UREA ANTAGONISTS OF P2Y1 RECEPTOR USEFUL IN THE TREATMENT OF THROMBOTIC CONDITIONS | BRISTOL MYERS SQUIBB COMPANY (US) | 2008-11-13 | — | — | US | disclosed |
| US-7388021-B2 | Urea antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions | BRISTOL MYERS SQUIBB COMPANY (US) | 2008-06-17 | — | — | US | disclosed |
| US-20050267119-A1 | Urea antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions | BRISTOL-MYERS SQUIBB COMPANY | 2005-12-01 | — | — | US | disclosed |
| EP-0025864-B1 | TETRAHYDROQUINOLINE DERIVATIVES, PROCESSES FOR THEIR PRODUCTION, THEIR USE AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM | CASSELLA Aktiengesellschaft (DE) | 1983-05-18 | — | — | EP | disclosed |
| US-4335123-A | HYPOTENSIVE AGENTS, ANTIARRHYTHMIA AGENTS | CASSELLA AKTIENGESELLSCHAFT (DE) | 1982-06-15 | — | — | US | disclosed |
| EP-0025864-A1 | Tetrahydroquinoline derivatives, processes for their production, their use and pharmaceutical preparations containing them | CASSELLA Aktiengesellschaft (DE) | 1981-04-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080280905-A1 | UREA ANTAGONISTS OF P2Y1 RECEPTOR USEFUL IN THE TREATMENT OF THROMBOTIC CONDITIONS | P2RY1, P2RY11, P2RY2 | ALDH1A1 1978/4885HPGD 676/4885MEN1 3173/4885 |
| US-20050267119-A1 | Urea antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions | P2RY1, P2RY11, P2RY2 | ALDH1A1 1978/4885HPGD 676/4885MEN1 3173/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.