SCHEMBL31453516

SCHEMBL31453516

Fc1ccc(/C=C/COc2ccccc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 4/20 0.53
AOC3 Q16853 1/20 0.50
MAOB P27338 3/20 0.48
MAOA P21397 2/20 0.48
IDO1 P14902 2/20 0.47
DRD2 P14416 1/20 0.45
HTR2A P28223 1/20 0.45
HTR2C P28335 1/20 0.45
HTR2B P41595 1/20 0.45
SIGMAR1 Q99720 1/20 0.45
RELA Q04206 1/20 0.44
KMT2A Q03164 2/20 0.44
MEN1 O00255 1/20 0.44
POLB P06746 1/20 0.44
PPARD Q03181 2/20 0.43
PPARA Q07869 2/20 0.43
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
PPARG P37231 1/20 0.43
LCK P06239 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31453512 0.90 NFE2L2 (0.47) NFE2L2AOC3MAOBMAOAIDO1
SCHEMBL11426742 0.87 IDO1 (0.61) NFE2L2AOC3MAOBMAOAIDO1
SCHEMBL1158152 0.87 IDO1 (0.61) NFE2L2AOC3MAOBMAOAIDO1
SCHEMBL1158153 0.87 IDO1 (0.61) NFE2L2AOC3MAOBMAOAIDO1
SCHEMBL24372558 0.84 AOC3 (0.52) AOC3MAOBMAOAIDO1RELA
SCHEMBL13582515 0.83 ALDH1A1 (0.50) NFE2L2MAOBMAOAKMT2AMEN1
SCHEMBL2231548 0.83 ALDH1A1 (0.50) NFE2L2MAOBMAOAKMT2AMEN1
SCHEMBL31453525 0.83 NFE2L2 (0.68) NFE2L2RELA
SCHEMBL2234412 0.82 AOC3 (0.50) AOC3MAOBMAOAIDO1RELA
SCHEMBL2234415 0.82 AOC3 (0.50) AOC3MAOBMAOAIDO1RELA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119930697-A Benzylidene o-halogenated Ru olefin metathesis catalyst and preparation and application thereof 中国石油天然气股份有限公司 2025-05-06 CN disclosed
CN-119930696-A Imidazole coordinated ruthenium carbene olefin metathesis catalyst, preparation and application thereof 中国石油天然气股份有限公司 2025-05-06 CN disclosed