Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26644511 | 0.82 | ALDH1A1 (0.47) | ALDH1A1TDP1TSHRSMN1; SMN2GAA | |
| SCHEMBL10126813 | 0.82 | ALDH1A1 (0.49) | ALDH1A1TDP1TSHRSMN1; SMN2GAA | |
| SCHEMBL10126809 | 0.82 | HTT (0.69) | ALDH1A1TDP1TSHRSMN1; SMN2GAA | |
| SCHEMBL28322852 | 0.82 | ALDH1A1 (0.70) | ALDH1A1TDP1TSHRSMN1; SMN2GAA | |
| SCHEMBL10035911 | 0.81 | HTT (0.47) | ALDH1A1TDP1TSHRSMN1; SMN2GAA | |
| SCHEMBL26983319 | 0.79 | ALDH1A1 (0.46) | ALDH1A1TDP1TSHRSMN1; SMN2GAA | |
| SCHEMBL10126803 | 0.78 | HTT (0.57) | ALDH1A1TDP1TSHRSMN1; SMN2GAA | |
| SCHEMBL6221391 | 0.78 | GAA (0.69) | ALDH1A1SMN1; SMN2GAACYP3A4HTT | |
| SCHEMBL242441 | 0.78 | GAA (0.69) | ALDH1A1SMN1; SMN2GAACYP3A4HTT | |
| SCHEMBL7049102 | 0.78 | GAA (0.60) | ALDH1A1TDP1TSHRSMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025016138-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | SUZHOU EOC MEDICAL RESEARCH CO., LTD. (CN) | 2025-01-23 | — | — | WO | disclosed |