Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Glycine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycine SCHEMBL37746 | 0.96 | — | — | |
| Glycine SCHEMBL5053459 | 0.96 | — | — | |
| Glycine SCHEMBL1650224 | 0.96 | GLRA1 (0.91) | — | |
| Glycine SCHEMBL6357710 | 0.96 | GLRA1 (0.91) | — | |
| Glycine SCHEMBL11056979 | 0.96 | GLRA1 (0.91) | — | |
| Glycine SCHEMBL1555637 | 0.96 | GLRA1 (0.91) | — | |
| Glycine SCHEMBL28861283 | 0.96 | GLRA1 (0.91) | — | |
| Glycine SCHEMBL3505988 | 0.96 | — | — | |
| Glycine SCHEMBL4884601 | 0.96 | — | — | |
| Glycine SCHEMBL433424 | 0.96 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2054539-B1 | METHOD FOR DEPOSITION OF CHROMIUM LAYERS AS HARD- CHROME PLATING, ELECTROPLATING BATH AND HARD- CHROME SURFACES | FRAUNHOFER GES FORSCHUNG (DE) | 2012-05-30 | — | — | EP | disclosed |
| US-20100075174-A1 | Method for deposition of chromium layers as hard-chrome plating, electroplating bath and hard-chrome surfaces | FRAUNHOFER-GESELLSCHAFT ZUR FORDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) | 2010-03-25 | — | — | US | disclosed |
| CN-101512047-A | Method for deposition of chromium layers as hard- chrome plating, electroplating bath and hard- chrome surfaces | FRAUNHOFER GES FORSCHUNG (DE) | 2009-08-19 | — | — | CN | disclosed |
| EP-2054539-A2 | METHOD FOR DEPOSITION OF CHROMIUM LAYERS AS HARD- CHROME PLATING, ELECTROPLATING BATH AND HARD- CHROME SURFACES | Fraunhofer-Gesellschaft zur Förderung der Angewandten Forschung e.V. (DE) | 2009-05-06 | — | — | EP | disclosed |
| WO-2008014987-A2 | METHOD FOR DEPOSITION OF CHROMIUM LAYERS AS HARD- CHROME PLATING, ELECTROPLATING BATH AND HARD- CHROME SURFACES | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) | 2008-02-07 | — | — | WO | disclosed |