Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 4/20 | 0.44 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.44 |
| ▸ | GSK3A | P49840 | 3/20 | 0.43 |
| ▸ | AURKA | O14965 | 2/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 10/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.38 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.36 |
| ▸ | PRKACA | P17612 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31455247 | 0.89 | PIN1 (0.46) | GSK3BPIN1GSK3AAURKAABCG2 | |
| SCHEMBL31455064 | 0.84 | GSK3B (0.45) | GSK3BPIN1GSK3AAURKAABCG2 | |
| SCHEMBL31420362 | 0.83 | GSK3B (0.47) | GSK3BPIN1GSK3AAURKAABCG2 | |
| SCHEMBL31455381 | 0.83 | GSK3B (0.47) | GSK3BPIN1GSK3AAURKAABCG2 | |
| SCHEMBL31455591 | 0.81 | GSK3B (0.39) | GSK3BPIN1GSK3AAURKAABCG2 | |
| SCHEMBL31455258 | 0.81 | GSK3B (0.45) | GSK3BPIN1GSK3AAURKAABCG2 | |
| SCHEMBL12100934 | 0.80 | GSK3B (0.57) | GSK3BPIN1GSK3AAURKAABCG2 | |
| SCHEMBL31455412 | 0.80 | GSK3B (0.43) | GSK3BPIN1GSK3AAURKAABCG2 | |
| SCHEMBL31455113 | 0.77 | PIN1 (0.47) | GSK3BPIN1GSK3AAURKAABCG2 | |
| SCHEMBL31455363 | 0.75 | GSK3B (0.43) | GSK3BPIN1GSK3AAURKAABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059577-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |