Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 4/20 | 0.47 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 9/20 | 0.43 |
| ▸ | GSK3A | P49840 | 3/20 | 0.43 |
| ▸ | AURKA | O14965 | 2/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | TYMS | P04818 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31420362 | 0.86 | GSK3B (0.47) | GSK3BPIN1ABCG2GSK3AAURKA | |
| SCHEMBL31455258 | 0.84 | GSK3B (0.45) | GSK3BPIN1ABCG2GSK3AAURKA | |
| SCHEMBL12100934 | 0.83 | GSK3B (0.57) | GSK3BPIN1ABCG2GSK3AAURKA | |
| SCHEMBL31455013 | 0.83 | GSK3B (0.44) | GSK3BPIN1ABCG2GSK3AAURKA | |
| SCHEMBL31455247 | 0.83 | PIN1 (0.46) | GSK3BPIN1ABCG2GSK3AAURKA | |
| SCHEMBL31455412 | 0.80 | GSK3B (0.43) | GSK3BPIN1ABCG2GSK3AAURKA | |
| SCHEMBL31455289 | 0.80 | PIK3CA (0.46) | GSK3BPIN1ABCG2PIK3CAPIK3CB | |
| SCHEMBL31455004 | 0.78 | ABCG2 (0.40) | GSK3BPIN1ABCG2MAPTMEN1 | |
| SCHEMBL27226936 | 0.77 | MAPT (0.49) | GSK3BABCG2GSK3AAURKAMAPT | |
| SCHEMBL31455064 | 0.77 | GSK3B (0.45) | GSK3BPIN1ABCG2GSK3AAURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059562-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS AND METHODS OF TREATING DISEASE USING SAME | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |
| WO-2025059577-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |