Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | GSTO1 | P78417 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | RNF4 | P78317 | 1/20 | 0.36 |
| ▸ | MAP2K7 | O14733 | 2/20 | 0.36 |
| ▸ | MALT1 | Q9UDY8 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3146681 | 0.86 | CHRNB4 (0.45) | FFAR4CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL3151018 | 0.85 | FFAR4 (0.40) | FFAR4CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL3147019 | 0.85 | FFAR4 (0.44) | FFAR4CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL3150647 | 0.84 | FFAR4 (0.40) | FFAR4CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL3257000 | 0.84 | FFAR4 (0.42) | FFAR4CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL3147054 | 0.83 | FFAR4 (0.38) | FFAR4CHRNB4CHRNA3CHRNA7 | |
| Hydrochloric Acid SCHEMBL3778862 | 0.82 | MAP2K7 (0.39) | ALDH1A1HTTSMN1; SMN2NPC1MITF | |
| SCHEMBL3773722 | 0.81 | GSTO1 (0.35) | ALDH1A1HTTSMN1; SMN2NPC1MITF | |
| SCHEMBL3151256 | 0.81 | FFAR4 (0.38) | SMN1; SMN2MAPTMEN1KMT2AFFAR4 | |
| SCHEMBL3145499 | 0.80 | ALDH1A1 (0.39) | ALDH1A1HTTSMN1; SMN2NPC1MITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979321-B9 | NOVEL PYRIDINYLAMINOALKYLENE- AND PYRIDINYLOXYALKYLENE-CYCLOPROPANAMINES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SERVIER LAB (FR) | 2010-02-17 | — | — | EP | disclosed |
| EP-1979321-B1 | NOVEL PYRIDINYLAMINOALKYLENE- AND PYRIDINYLOXYALKYLENE-CYCLOPROPANAMINES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SERVIER LAB (FR) | 2009-07-29 | — | — | EP | disclosed |