Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | BCR | P11274 | 1/20 | 0.38 |
| ▸ | PRKCA | P17252 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | TLR4 | O00206 | 1/20 | 0.37 |
| ▸ | TLR2 | O60603 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31455383 | 0.83 | MAPT (0.43) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL8302605 | 0.76 | MAPT (0.62) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL13736898 | 0.76 | MAPT (0.49) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL31455538 | 0.74 | ABL1 (0.47) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL25877483 | 0.73 | MAPT (0.43) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL31455452 | 0.72 | ABCG2 (0.39) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL12643379 | 0.71 | MAPT (0.69) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL6832746 | 0.70 | MEN1 (0.61) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL31455238 | 0.69 | TDP1 (0.49) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL18553627 | 0.68 | MAPT (0.46) | MEN1KMT2AMAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059577-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |