Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 5/20 | 0.44 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.43 |
| ▸ | BCL2 | P10415 | 2/20 | 0.42 |
| ▸ | BECN1 | Q14457 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.38 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31455844 | 0.85 | CYP1A2 (0.41) | BCL2PKMHDAC1NPC1NFKB1 | |
| SCHEMBL31455424 | 0.85 | NPC1 (0.44) | PKMHDAC1NPC1NFKB1RAB9A | |
| SCHEMBL31455318 | 0.84 | HDAC1 (0.50) | BCL2HDAC1GSK3BDYRK1AMAP4K4 | |
| SCHEMBL31455499 | 0.83 | MAPT (0.39) | HDAC1NPC1RAB9ASMN1; SMN2PRMT1 | |
| SCHEMBL31455389 | 0.82 | MEN1 (0.43) | SMN1; SMN2PRMT1 | |
| SCHEMBL31420343 | 0.82 | PRMT1 (0.41) | BCL2BECN1PKMHDAC1GSK3B | |
| SCHEMBL14183129 | 0.77 | BCL2 (0.53) | BCL2HDAC1GSK3BDYRK1ACYP17A1 | |
| SCHEMBL31455428 | 0.77 | FGFR4 (0.44) | NPC1NFKB1RAB9ANFKB2RELA | |
| SCHEMBL3236492 | 0.76 | ABCB1 (0.60) | ABCB1ABCC1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5868990 | 0.76 | ABCB1 (0.60) | ABCB1ABCC1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059577-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |