Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.44 |
| ▸ | RAB9A | P51151 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31455844 | 0.88 | CYP1A2 (0.41) | NPC1RAB9AMAPTSMN1; SMN2LMNA | |
| SCHEMBL31455388 | 0.86 | PRMT1 (0.46) | NPC1RAB9AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL31455150 | 0.85 | ABCB1 (0.44) | NPC1RAB9ASMN1; SMN2HDAC1PRMT1 | |
| SCHEMBL31455499 | 0.85 | MAPT (0.39) | NPC1RAB9AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL31455389 | 0.85 | MEN1 (0.43) | MAPTSMN1; SMN2CASP3HTTSENP7 | |
| SCHEMBL31455675 | 0.83 | MAPT (0.54) | NPC1RAB9AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL31455162 | 0.81 | KMT2A (0.42) | NPC1RAB9AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL31455428 | 0.79 | FGFR4 (0.44) | NPC1RAB9AMAPTSMN1; SMN2MAPK1 | |
| SCHEMBL31455251 | 0.78 | PRMT1 (0.43) | NPC1RAB9AMAPTSMN1; SMN2HDAC1 | |
| SCHEMBL31455445 | 0.77 | MAPK1 (0.40) | NPC1RAB9AMAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059562-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS AND METHODS OF TREATING DISEASE USING SAME | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |
| WO-2025059577-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |