Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | NAMPT | P43490 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31455191 | 0.93 | GAA (0.61) | ALDH1A1MAPTGAAHTTKMT2A | |
| SCHEMBL28813844 | 0.82 | GAA (0.85) | ALDH1A1MAPTGAAHTTKMT2A | |
| SCHEMBL31455409 | 0.82 | ALDH1A1 (0.75) | ALDH1A1MAPTGAAHTTKMT2A | |
| SCHEMBL8483965 | 0.80 | MAPT (0.65) | MAPTKMT2A | |
| SCHEMBL14574134 | 0.80 | GAA (0.97) | ALDH1A1GAAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL13841221 | 0.80 | GAA (0.63) | ALDH1A1MAPTGAAHTTKMT2A | |
| SCHEMBL596038 | 0.79 | MAPT (1.00) | ALDH1A1MAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL14574146 | 0.79 | GAA (0.74) | ALDH1A1MAPTGAAHTTKMT2A | |
| SCHEMBL9435700 | 0.78 | GAA (1.00) | ALDH1A1GAAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL14574147 | 0.78 | GAA (0.61) | ALDH1A1MAPTGAAHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059577-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |