Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | HTT | P42858 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | NAMPT | P43490 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31455212 | 0.93 | ALDH1A1 (0.68) | GAAMAPTALDH1A1HTTKMT2A | |
| SCHEMBL31455177 | 0.83 | ALDH1A1 (0.64) | GAAMAPTALDH1A1HTTKMT2A | |
| SCHEMBL13841221 | 0.83 | GAA (0.63) | GAAMAPTALDH1A1HTTKMT2A | |
| SCHEMBL14413881 | 0.78 | GAA (0.67) | GAAMAPTALDH1A1KMT2ANAMPT | |
| SCHEMBL14711312 | 0.78 | MAPT (0.85) | MAPTALDH1A1LMNASMN1; SMN2POLB | |
| SCHEMBL14712107 | 0.78 | MAPT (0.85) | MAPTALDH1A1LMNASMN1; SMN2POLB | |
| SCHEMBL28813844 | 0.77 | GAA (0.85) | GAAMAPTALDH1A1HTTKMT2A | |
| SCHEMBL9435700 | 0.76 | GAA (1.00) | GAAALDH1A1KMT2AMEN1RAB9A | |
| SCHEMBL31455642 | 0.76 | ALDH1A1 (0.50) | GAAMAPTALDH1A1HTTKMT2A | |
| SCHEMBL8483965 | 0.76 | MAPT (0.65) | MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059577-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |