Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 2/20 | 0.49 |
| ▸ | GSK3B | P49841 | 2/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 8/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.44 |
| ▸ | TYK2 | P29597 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | WNT1 | P04628 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31455279 | 0.94 | ABL1 (0.48) | ABL1GSK3BDYRK1AADORA2AADORA2B | |
| SCHEMBL31455073 | 0.89 | HDAC1 (0.50) | GSK3BDYRK1AADORA2AADORA1HDAC1 | |
| SCHEMBL31455538 | 0.87 | ABL1 (0.47) | ABL1GSK3BDYRK1AADORA2AADORA2B | |
| SCHEMBL31455065 | 0.76 | ABCB1 (0.44) | GSK3BDYRK1AADORA2AADORA1HDAC1 | |
| SCHEMBL31455325 | 0.75 | HDAC1 (0.41) | GSK3BADORA2AADORA1HDAC1HDAC2 | |
| SCHEMBL31455476 | 0.72 | AKT1 (0.44) | ABL1GSK3BDYRK1AKDM4EHSD17B10 | |
| SCHEMBL31455042 | 0.72 | AKT1 (0.44) | ABL1GSK3BDYRK1AKDM4EHSD17B10 | |
| SCHEMBL31455274 | 0.71 | HDAC1 (0.38) | GSK3BADORA2AADORA1HDAC1HDAC2 | |
| SCHEMBL31455813 | 0.70 | HDAC2 (0.52) | HDAC1HDAC2HDAC3 | |
| SCHEMBL10287930 | 0.67 | ABL1 (1.00) | ABL1GSK3BDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059577-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |