Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 10/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 10/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.45 |
| ▸ | GSK3B | P49841 | 2/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | WNT1 | P04628 | 1/20 | 0.39 |
| ▸ | TYK2 | P29597 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31455220 | 0.94 | ABL1 (0.49) | ABL1HDAC1HDAC2HDAC3GSK3B | |
| SCHEMBL31455073 | 0.83 | HDAC1 (0.50) | HDAC1HDAC2HDAC3GSK3BDYRK1A | |
| SCHEMBL31455538 | 0.83 | ABL1 (0.47) | ABL1GSK3BDYRK1AKDM4EHSD17B10 | |
| SCHEMBL31455476 | 0.75 | AKT1 (0.44) | ABL1GSK3BDYRK1AKDM4EHSD17B10 | |
| SCHEMBL31455042 | 0.75 | AKT1 (0.44) | ABL1GSK3BDYRK1AKDM4EHSD17B10 | |
| SCHEMBL31455065 | 0.71 | ABCB1 (0.44) | HDAC1HDAC2HDAC3GSK3BDYRK1A | |
| SCHEMBL31455325 | 0.71 | HDAC1 (0.41) | HDAC1HDAC2HDAC3GSK3BKDM4E | |
| SCHEMBL31455487 | 0.70 | HDAC1 (0.36) | ABL1HDAC1HDAC2HDAC3GSK3B | |
| SCHEMBL31455134 | 0.68 | MEN1 (0.44) | ABL1HDAC1HDAC2KDM4ENPC1 | |
| SCHEMBL31455411 | 0.67 | HDAC1 (0.46) | ABL1HDAC1HDAC2HDAC3GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059577-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |