Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.41 |
| ▸ | GSK3B | P49841 | 3/20 | 0.41 |
| ▸ | GSK3A | P49840 | 2/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 9/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 7/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31455274 | 0.89 | HDAC1 (0.38) | HDAC1HDAC2GSK3BGSK3AADORA1 | |
| SCHEMBL31455204 | 0.86 | GSK3B (0.38) | GSK3BGSK3AADORA1ADORA2AADORA3 | |
| SCHEMBL31455490 | 0.85 | HDAC1 (0.40) | HDAC1HDAC2GSK3BGSK3AADORA1 | |
| SCHEMBL31455491 | 0.85 | HDAC1 (0.40) | HDAC1HDAC2GSK3BGSK3AADORA1 | |
| SCHEMBL31455694 | 0.82 | HDAC1 (0.46) | HDAC1HDAC2GSK3BGSK3AADORA1 | |
| SCHEMBL31455411 | 0.82 | HDAC1 (0.46) | HDAC1HDAC2GSK3BGSK3AADORA1 | |
| SCHEMBL31455487 | 0.82 | HDAC1 (0.36) | HDAC1HDAC2GSK3BGSK3AADORA1 | |
| SCHEMBL31455364 | 0.81 | ADORA1 (0.42) | HDAC1HDAC2GSK3BGSK3AADORA1 | |
| SCHEMBL31455073 | 0.81 | HDAC1 (0.50) | HDAC1HDAC2GSK3BADORA1ADORA2A | |
| SCHEMBL31455285 | 0.75 | HDAC2 (0.40) | HDAC1HDAC2GSK3BGSK3AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059577-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |