Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 13/20 | 0.46 |
| ▸ | BRAF | P15056 | 7/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31455202 | 0.86 | KDR (0.44) | KDRBRAFKMT2ANPC1TP53 | |
| SCHEMBL31455832 | 0.80 | F10 (0.47) | KMT2ANPC1TP53RAB9AMEN1 | |
| SCHEMBL31455523 | 0.73 | ABL1 (0.50) | KMT2ANPC1TP53PKMRAB9A | |
| SCHEMBL31455390 | 0.73 | HDAC2 (0.56) | NPC1RAB9AABL1 | |
| SCHEMBL31455455 | 0.72 | KMT2A (0.45) | KMT2ANPC1TP53PKMRAB9A | |
| SCHEMBL31455161 | 0.72 | KMT2A (0.46) | KMT2ANPC1TP53PKMRAB9A | |
| SCHEMBL31455162 | 0.70 | KMT2A (0.42) | BRAFKMT2ANPC1TP53PKM | |
| SCHEMBL374880 | 0.67 | ABL1 (0.54) | KMT2ANPC1TP53PKMRAB9A | |
| SCHEMBL374881 | 0.67 | ABL1 (0.54) | KMT2ANPC1TP53PKMRAB9A | |
| SCHEMBL3492544 | 0.67 | HDAC1 (0.52) | NPC1RAB9AHSD17B10ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059577-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |