Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | WNT1 | P04628 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31455417 | 0.82 | PRMT1 (0.39) | NPC1RAB9AKMT2AGSK3BDYRK1A | |
| SCHEMBL31455339 | 0.82 | ABL1 (0.45) | NPC1RAB9ATP53PKMHSD17B10 | |
| SCHEMBL31455494 | 0.80 | HDAC1 (0.44) | NPC1RAB9ATP53PKMHSD17B10 | |
| SCHEMBL31455084 | 0.77 | MAPT (0.39) | NPC1RAB9ATP53PKMHSD17B10 | |
| SCHEMBL31455333 | 0.76 | MAPT (0.38) | NPC1RAB9ATP53PKMHSD17B10 | |
| SCHEMBL31371426 | 0.76 | MEN1 (0.41) | RAB9AKMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL31455353 | 0.75 | MAPT (0.38) | RAB9AKMT2AGSK3BALDH1A1MAPT | |
| SCHEMBL31455162 | 0.72 | KMT2A (0.42) | NPC1RAB9ATP53PKMHSD17B10 | |
| SCHEMBL31455523 | 0.72 | ABL1 (0.50) | NPC1RAB9ATP53PKMHSD17B10 | |
| SCHEMBL31455202 | 0.70 | KDR (0.44) | NPC1RAB9ATP53PKMHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059577-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |