Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.42 |
| ▸ | WNT1 | P04628 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31455390 | 0.86 | HDAC2 (0.56) | HDAC1HDAC2MAPK8MAPK10MAPK14 | |
| SCHEMBL31455339 | 0.84 | ABL1 (0.45) | WNT1GSK3BDYRK1AABL1MAPT | |
| SCHEMBL31455084 | 0.84 | MAPT (0.39) | WNT1GSK3BDYRK1AABL1MAPT | |
| SCHEMBL31455333 | 0.84 | MAPT (0.38) | WNT1GSK3BDYRK1AABL1MAPT | |
| SCHEMBL31455801 | 0.81 | NPC1 (0.46) | ABL1MAPTNPC1RAB9APTPN1 | |
| SCHEMBL31455292 | 0.81 | PRMT1 (0.41) | GSK3BDYRK1AMAPTNPC1RAB9A | |
| SCHEMBL31455818 | 0.81 | PRMT1 (0.41) | GSK3BDYRK1AMAPTNPC1RAB9A | |
| SCHEMBL31455273 | 0.80 | NPC1 (0.40) | WNT1GSK3BDYRK1AMAPTNPC1 | |
| SCHEMBL31455261 | 0.78 | PTPN2 (0.50) | ABL1NPC1RAB9APTPN2PTPN1 | |
| SCHEMBL18380144 | 0.75 | HDAC1 (0.71) | HDAC1HDAC2MAPK8MAPK10MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059577-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |