Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31455496 | 0.72 | GAA (0.33) | HTTKMT2AGAAMAPTNPSR1 | |
| SCHEMBL8531001 | 0.71 | APLNR (0.39) | APLNRPTPN1MAPTNPSR1ALDH1A1 | |
| SCHEMBL16137372 | 0.70 | EPHX2 (0.40) | — | |
| SCHEMBL294509 | 0.69 | — | — | |
| SCHEMBL13738558 | 0.68 | CHRNB2 (0.50) | SMN1; SMN2GAAALDH1A1 | |
| SCHEMBL28776896 | 0.68 | APLNR (0.37) | APLNRPTPN1MAPTNPSR1 | |
| SCHEMBL21946031 | 0.68 | APLNR (0.37) | APLNRPTPN1MAPTNPSR1 | |
| SCHEMBL19284416 | 0.67 | — | — | |
| SCHEMBL19284415 | 0.67 | — | — | |
| SCHEMBL31455461 | 0.67 | TP53 (0.34) | SMN1; SMN2GAAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059577-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |