Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | ANPEP | P15144 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31455239 | 0.81 | GAA (0.41) | GAAMAPTNPSR1HTTTSHR | |
| SCHEMBL812670 | 0.76 | ATM (0.36) | GAAMAPTNPSR1HTTTSHR | |
| SCHEMBL9873481 | 0.67 | POLB (0.42) | MAPTHTTKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL9127405 | 0.67 | POLB (0.42) | MAPTHTTKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL9957179 | 0.67 | — | — | |
| SCHEMBL7305696 | 0.67 | BRD4 (0.38) | TSHRALDH1A1CYP1A2MMP2ANPEP | |
| SCHEMBL7305695 | 0.67 | BRD4 (0.38) | TSHRALDH1A1CYP1A2MMP2ANPEP | |
| SCHEMBL7305703 | 0.67 | BRD4 (0.38) | TSHRALDH1A1CYP1A2MMP2ANPEP | |
| SCHEMBL11807904 | 0.67 | ALDH1A1 (0.38) | GAAMAPTNPSR1HTTTSHR | |
| SCHEMBL5706652 | 0.66 | HTT (0.41) | HTTTSHRKMT2AALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059577-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |