Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | ANPEP | P15144 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31455397 | 0.81 | GAA (0.37) | GAAMAPTNPSR1TSHRKMT2A | |
| SCHEMBL31455072 | 0.77 | APLNR (0.36) | MAPTTSHRKMT2AALDH1A1HTT | |
| SCHEMBL11804151 | 0.77 | ALDH1A1 (0.31) | MAPTTSHRALDH1A1KDM4E | |
| SCHEMBL9851192 | 0.75 | GAA (0.47) | GAAMAPTNPSR1TSHRALDH1A1 | |
| SCHEMBL2013946 | 0.75 | ATM (0.37) | GAAMAPTNPSR1TSHRKMT2A | |
| SCHEMBL2505350 | 0.75 | ATM (0.37) | GAAMAPTNPSR1TSHRKMT2A | |
| SCHEMBL9851194 | 0.74 | GAA (0.46) | GAAMAPTNPSR1TSHRALDH1A1 | |
| SCHEMBL2014678 | 0.72 | THRB (0.41) | GAAMAPTNPSR1TSHRKMT2A | |
| SCHEMBL11807904 | 0.72 | ALDH1A1 (0.38) | GAAMAPTNPSR1TSHRKMT2A | |
| SCHEMBL25541264 | 0.71 | ATM (0.37) | GAAMAPTNPSR1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059577-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |