Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 4/20 | 0.44 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | ATR | Q13535 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31455066 | 0.97 | FLT3 (0.41) | FLT3CCNE1CDK2ATRGSK3B | |
| SCHEMBL31454993 | 0.78 | PRMT1 (0.40) | ATRGSK3BMAPTMEN1CYP1A2 | |
| SCHEMBL31420362 | 0.78 | GSK3B (0.47) | GSK3BPIN1MAPTMEN1CYP1A2 | |
| SCHEMBL31455289 | 0.77 | PIK3CA (0.46) | GSK3BPIN1MAPTMEN1CYP1A2 | |
| SCHEMBL31455333 | 0.76 | MAPT (0.38) | GSK3BMAPTMEN1CYP1A2CYP3A4 | |
| SCHEMBL31455040 | 0.75 | PRMT1 (0.40) | GSK3BMAPTMEN1CYP1A2CYP3A4 | |
| SCHEMBL31455246 | 0.74 | BRD4 (0.37) | GSK3BPIN1MAPTMEN1CYP1A2 | |
| SCHEMBL31455084 | 0.73 | MAPT (0.39) | GSK3BMAPTMEN1CYP1A2CYP3A4 | |
| SCHEMBL31455353 | 0.67 | MAPT (0.38) | GSK3BPIN1MAPTMEN1CYP1A2 | |
| SCHEMBL9984336 | 0.63 | MAPT (0.52) | GSK3BTDP1PIN1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059577-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |