Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 1/20 | 0.46 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.46 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31420362 | 0.89 | GSK3B (0.47) | MEN1KMT2AGSK3BABCG2PIN1 | |
| SCHEMBL31455381 | 0.80 | GSK3B (0.47) | PIK3CAPIK3CBPIK3CGMEN1KMT2A | |
| SCHEMBL31455246 | 0.78 | BRD4 (0.37) | PIK3CAMEN1KMT2AGSK3BPIN1 | |
| SCHEMBL31455066 | 0.78 | FLT3 (0.41) | PIK3CAMEN1KMT2AGSK3BPIN1 | |
| SCHEMBL31455438 | 0.77 | FLT3 (0.44) | RAB9AMEN1KMT2AGSK3BPIN1 | |
| SCHEMBL27226100 | 0.76 | KMT2A (0.50) | PIK3CAPIK3CBPIK3CGHTTRAB9A | |
| SCHEMBL31455292 | 0.76 | PRMT1 (0.41) | PIK3CAPIK3CBPIK3CGALDH1A1RAB9A | |
| SCHEMBL18376192 | 0.74 | TDP1 (0.43) | PIK3CAPIK3CBPIK3CGALDH1A1RAB9A | |
| SCHEMBL31455258 | 0.74 | GSK3B (0.45) | MEN1KMT2AGSK3BABCG2PIN1 | |
| SCHEMBL31455353 | 0.73 | MAPT (0.38) | PIK3CAALDH1A1HTTRAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059577-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |
| WO-2025059562-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS AND METHODS OF TREATING DISEASE USING SAME | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |